Basisforschung und experimentelle Wissenschaft Hyaluronsäure

Watson A.L. et al. (2022):

Hyaluronic Acid-Based Antibacterial Hydrogels for Use as Wound Dressings. | ACS Appl Bio Mater. 2022 Nov 16

Corrêa M. E. A. B. et al. (2022):

Effects of the Application of Decellularized Amniotic Membrane Solubilized with Hyaluronic Acid on Wound Healing. Ann Biomed Eng. 2022 Jul 8. doi: 10.1007/s10439-022-03008-w

Elgamal A., Amin L. (2022):

EVALUATION OF TOPICAL APPLICATION OF PLATELETS RICH PLASMA AND HYALURONIC ACID ON THE HEALING OF EXPERIMENTALLY INDUCED TONGUE ULCER. E.D.J. Vol. 68, No. 1, 355:369,

Figueira T.G. . et al. (2022):

Development, characterization and in vivo evaluation of the ointment containing hyaluronic acid for potential wound healing applications. J Biomater Sci Polym Ed. 2022 Aug;33(12):1511-1530

Najim S.M. et al. (2022):

Estimation of the healing effects of the topical use of MEBO and hyaluronic acid gel in the burned rats. Journal of Advanced Pharmacy Education & Research, Apr-Jun 2022, Vol 12, Issue 2, p 91-97

Song A., Fawzy A. (2022):

Chang K. C. et al. (2021):

Effects of Hinokitiol and Dicalcium Phosphate on the Osteoconduction and Antibacterial Activity of Gelatin-Hyaluronic Acid Crosslinked Hydrogel Membrane In Vitro. Pharmaceuticals 2021, 14(8), 802

Cho J. R. et al. (2021):

Efficacy of hyaluronic acid film on perianal wound healing in a rat model
Ann Surg Treat Res. 2021 Oct;101(4):206-213

Filippis A. et al. (2021):

Q-switched Nd-YAG laser alone and in combination with innovative hyaluronic acid gels improve keratinocytes wound healing in vitro
Lasers Med Sci. 2021 Jul;36(5):1047-1057

Gonçalves R. C. et al. (2021):

Carboxymethyl chitosan hydrogel formulations enhance the healing process in experimental partial-thickness (second-degree) burn wound healing
Acta Cir Bras. 2021; 36(3): e360303

Hauck S. et al. (2021):

Collagen/hyaluronan based hydrogels releasing sulfated hyaluronan improve dermal wound healing in diabetic mice via reducing inflammatory macrophage activity
Bioact Mater. 2021 Apr 30;6(12):4342-4359

Hu B. et al. (2021):

An intrinsically bioactive hydrogel with on-demand drug release behaviors for diabetic wound healing. Bioact Mater. 2021 May 16;6(12):4592-4606

Kawano Y. et al. (2021):

Wound Healing Promotion by Hyaluronic Acid: Effect of Molecular Weight on Gene Expression and In Vivo Wound Closure.
Pharmaceuticals (Basel). 2021 Mar 28;14(4):301

Leite M. N. et al. (2021):

Efficacy of 0.2% hyaluronic acid in the healing of skin abrasions in rats
Heliyon. 2021 Jul 13;7(7):e07572

Pak C. S. et al. (2021):

Effects of a Catechol-Functionalized Hyaluronic Acid Patch Combined with Human Adipose-Derived Stem Cells in Diabetic Wound Healing
Int J Mol Sci. 2021 Mar 5;22(5):2632

Park C. S. et al. (2021):

Objective analysis of volume restoration in atrophic acne scars and skin pores: a split study using human stem cell-conditioned media
J Dermatolog Treat. 2021 Feb;32(1):73-77

Pavlik V. et al. (2021):

Silver distribution in chronic wounds and the healing dynamics of chronic wounds treated with dressings containing silver and octenidine
The FASEB Journal. 2021;00:e21580

Shirakata Y. et al. (2021):

Periodontal wound healing/regeneration of two-wall intrabony defects following reconstructive surgery with cross-linked hyaluronic acid-gel with or without a collagen matrix: a preclinical study in dogs
The FASEB Journal. 2021;00:e21580

Wei S. et al. (2021):

A composite hydrogel with co-delivery of antimicrobial peptides and platelet-rich plasma to enhance healing of infected wounds in diabetes
Acta Biomater. 2021 Apr 1;124:205-218

Xing Y. et al. (2021):

Human foreskin-derived dermal stem/progenitor cell-conditioned medium combined with hyaluronic acid promotes extracellular matrix regeneration in diabetic wounds
Stem Cell Res Ther. 2021 Jan 9;12(1):49

Yang H. et al. (2021):

Modulation of macrophages by a paeoniflorin-loaded hyaluronic acid-based hydrogel promotes diabetic wound healing Mater Today Bio. 2021 Sep 21;12:100139

Zamboni F. et al. (2021):

On the bacteriostatic activity of hyaluronic acid composite films
Carbohydr Polym. 2021 May 15;260:117803

Ahmadian E. et al. (2020):

The Potential Applications of Hyaluronic Acid Hydrogels in Biomedicine
Drug Res (Stuttg). 2020 Jan;70(1):6-11

Buhren, B.A et al. (2020):

Dose- and time-dependent effects of hyaluronidase on structural cells and the extracellular matrix of the skin.
Eur J Med Res 2020:25 (60)

Cortes H. et al. (2020):

Dong Y. et al. (2020):

Conformable hyaluronic acid hydrogel delivers adipose-derived stem cells and promotes regeneration of burn injury.
Acta Biomater. 2020, 108, 56–66

Eskandarinia A. et al. (2020):

A propolis enriched polyurethane-hyaluronic acid nanofibrous wound dressing with remarkable antibacterial and wound healing activities
Int J Biol Macromol. 2020 Jan 27;149:467-476

Hadisi Z. et al. (2020):

Hyaluronic Acid (HA)-Based Silk Fibroin/Zinc Oxide Core-Shell Electrospun Dressing for Burn Wound Management
Macromol Biosci. 2020 Apr;20(4):e1900328

Hameed M. A. et al. (2020):

Role of Hyaluronic Acid in Modulating Wound Healing Progression
Sys Rev Pharm 2020;11(11):1844-1850

Iacopetti I. et al. (2020):

Hyaluronic acid, Manuka honey and Acemannan gel: Wound-specific applications for skin lesions
Res Vet Sci. 2020 Jan 11;129:82-89

Ilomuanya M. et al. (2020):

Silver Sulphadiazine- xanthan gum- hyaluronic Acid Composite Hydrogel for Wound Healing: Formulation Development and in vivo Evaluation
Nig. J. Pharm.Res. 2020, 16 (1) pp. 21-29

Olmos-Zuñiga R.J. et al. (2020):

Treatment with Hyaluronic Acid and Collagen-Polyvinylpyrrolidone Improves Extracellular Matrix Assembly for Scarring after Tracheal Resection
Biomed Res Int. 2020 Aug 27;2020:3964518

Sha Liu et al. (2020):

Absorbable Thioether Grafted Hyaluronic Acid Nanofibrous Hydrogel for Synergistic Modulation of Inflammation Microenvironment to Accelerate Chronic Diabetic Wound Healing.
Adv Healthc Mater. 2020 Jun;9(11):e2000198

Sha Liu et al. (2020):

Dual Cross-linked HHA Hydrogel Supplies and Regulates MΦ2 for Synergistic Improvement of Immunocompromise and Impaired Angiogenesis to Enhance Diabetic Chronic Wound Healing
Biomacromolecules. 2020 Sep 14;21(9):3795-3806

Sierra‐Sánchez Á. et al. (2020):

Hyaluronic acid biomaterial for human tissue-engineered skin substitutes: Preclinical comparative in vivo study of wound healing
J Eur Acad Dermatol Venereol. 2020 Oct;34(10):2414-2427

Silvestro I. et al. (2020):

Hyaluronic Acid Reduces Bacterial Fouling and Promotes Fibroblasts' Adhesion onto Chitosan 2D-Wound Dressings
Int J Mol Sci. 2020 Mar 18;21(6):2070

Singampalli K. L. et al. (2020):

The Role of an IL-10/Hyaluronan Axis in Dermal Wound Healing
Front Cell Dev Biol. 2020 Jul 17;8:636

Spearman B.J. et al. (2020):

Tunable methacrylated hyaluronic acid-based hydrogels as scaffolds for soft tissue engineering applications. J Biomed Mater Res A. 2020 Feb;108(2):279-291

Tamer T.M. et al. (2020):

Enhancement of wound healing by chitosan/hyaluronan polyelectrolyte membrane loaded with glutathione: In vitro and in vivo evaluations
J Biotechnol. 2020 Feb 20;310:103-113

Taskan M. M. et al. (2020):

Hyaluronic acid with antioxidants improve wound healing in rats
Biotech Histochem. 2020 Oct 13;1-10

Yu Q.H. et al. (2020):

Mussel-Inspired Adhesive Polydopamine-Functionalized Hyaluronic Acid Hydrogel with Potential Bacterial Inhibition. Glob Chall. 2019 Nov 18;4(2):1900068

Zhao X. et al. (2020):

Hyaluronic acid/lysozyme self-assembled coacervate to promote cutaneous wound healing. Biomater Sci. 2020 Mar 17;8(6):1702-1710

Chen R.F. et al. (2019):

Hyaluronic Acid-Povidone-Iodine Compound Facilitates Diabetic Wound Healing in a Streptozotocin-Induced Diabetes Rodent Model
Plast Reconstr Surg. 2019 May;143(5):1371-1382

D'Agostino A. et al. (2019):

In Vitro Evaluation of Novel Hybrid Cooperative Complexes in a Wound Healing Model: A Step Toward Improved Bioreparation
Int J Mol Sci. 2019 Sep 24;20(19)

Eskandarinia A. et al. (2019):

Cornstarch-based wound dressing incorporated with hyaluronic acid and propolis: In vitro and in vivo studies
Carbohydr Polym. 2019 Jul 15;216:25-35

Gao Z. et al. (2019):

A redox-responsive hyaluronic acid-based hydrogel for chronic wound management
J Mater Chem B. 2019 Dec 21;7(47):7494-7501

La Gatta A. et al. (2019):

A biophysically-defined hyaluronic acid-based compound accelerates migration and stimulates the production of keratinocyte-derived neuromodulators
Cell Adh Migr. 2019 Dec;13(1):23-32

López-Ruiz E. et al. (2019):

Advances of hyaluronic acid in stem cell therapy and tissue engineering, including current clinical trials
Carbohydr Polym. 2019 Nov 1;223:115023

Makvandi P et al. (2019):

Biosynthesis and characterization of antibacterial thermosensitive hydrogels based on corn silk extract, hyaluronic acid and nanosilver for potential wound healing
Carbohydr Polym. 2019 Nov 1;223:115023

Nyman E. et al. (2019):

Hyaluronic Acid Accelerates Re- epithelialization and Alters Protein Expression in a Human Wound Model
Plast Reconstr Surg Glob Open. 2019 May 1;7(5):e2221

Pandith A.H. (2019):

Periodate oxidized hyaluronic acid- based hydrogel scaffolds for tissue engineering applications
Int J Biol Macromol. 2019 Sep 15;137:853-869

Vigani B. et al. (2019):

Hyaluronic acid and chitosan-based nanosystems: a new dressing generation for wound care
Expert Opin Drug Deliv. 2019 Jul;16(7):715-740

Ying H. et al. (2019):

In situ formed collagen-hyaluronic acid hydrogel as biomimetic dressing for promoting spontaneous wound healing
Mater Sci Eng C Mater Biol Appl. 2019 Aug;101:487-498

Berce C. et al. (2018):

Cutaneous wound healing using polymeric surgical dressings based on chitosan, sodium hyaluronate and resveratrol. A preclinical experimental study.
Colloids Surf B Biointerfaces. 2018 Mar 1;163:155-166

Hämäläinen L. et al. (2018):

Hyaluronan metabolism enhanced during epidermal differentiation is suppressed by vitamin C
Br J Dermatol. 2018 Sep;179(3):651-661

Hong L. et al. (2018):

Hyaluronic acid (HA)-based hydrogels for full-thickness wound repairing and skin regeneration
J Mater Sci Mater Med. 2018 Sep 8;29(9):150

Horch R. E. et al. (2018):

Keratinocyte Monolayers on Hyaluronic Acid Membranes as "Upside-Down" Grafts Reconstitute Full-Thickness Wounds
Med Sci Monit. 2019; 25: 6702–6710

Huerta-Ángeles G. et al. (2018):

An Effective Translation: The Development of Hyaluronan-Based Medical Products From the Physicochemical, and Preclinical Aspects
Front Bioeng Biotechnol. 2018; 6:62

Kawano Y. et al. (2018):

Acceleration of wound healing induced by hyaluronic acid
New Biotechnology 2018; 44:S104

Laranetta E. et al. (2018):

Synthesis and characterization of hyaluronic acid hydrogels crosslinked using a solvent-free process for potential biomedical applications
Carbohydr Polym. 2018 Feb 1;181:1194-1205

Luttrell T. et al. (2018):

Novel Use of a Biologically Active-Prefabricated-Random-Three-Dimensional-Polymer Scaffold of Hyaluronic Acid (HYAFF) to Facilitate Complicated Wound Closure
Burns, Infections and Wound Management pp 213-247

Passi A. et al. (2018):

Hyaluronan is a key regulator of skin homeostasis and wound healing
Br J Dermatol. 2018 Sep;179(3):558-559

Tamer T.M. et al. (2018):

Chitosan/hyaluronan/edaravone membranes for anti-inflammatory wound dressing: In vitro and in vivo evaluation studies
Mater Sci Eng C Mater Biol Appl. 2018 Sep 1;90:227-235

Tamer T.M. et al. (2018):

MitoQ Loaded Chitosan-Hyaluronan Composite Membranes for Wound Healing
Materials (Basel). 2018 Apr 7;11(4)

Tarusha L. et al. (2018):

Alginate membranes loaded with hyaluronic acid and silver nanoparticles to foster tissue healing and to control bacterial contamination of non-healing wounds.
J Mater Sci Mater Med. 2018 Feb 2;29(3):22

Tracy L. A. et al. (2018):

Extracellular Matrix and Dermal Fibroblast Function in the Healing Wound
Adv Wound Care (New Rochelle). 2016 Mar 1;5(3):119-136

Rüther L. et al. (2017):

Hyaluronan als Schlüssel zur schnelleren Wundheilung in humanen 3‐D-Vollhautmodellen. Hautarzt 2017 · 68:987–993

Wu S. et al. (2017):

Evaluation of gelatin-hyaluronic acid composite hydrogels for accelerating wound healing. J Biomater Appl. 2017 May;31(10):1380-1390

De Oliveira J.D et al. (2016):

Genetic basis for hyper production of hyaluronic acid in natural and engineered microorganisms. Microb Cell Fact. 2016; 15: 119

Crisci A. et al. (2016):

Comparison between HMPA treatment and homologous cadaver skin in chronic ulcerative lesions. Acta Vulnologica 2016 March;14(1):44-9

Fouda M. M. G. et al. (2016):

Wound healing of different molecular weight of hyaluronan; in-vivo study
Int J Biol Macromol. 2016 Aug;89:582-91

Hemshekhar M. et al. (2016):

Emerging roles of hyaluronic acid bioscaffolds in tissue engineering and regenerative medicine
Int J Biol Macromol. 2016 May;86:917-28

Litwiniuk M. et al. (2016):

Hyaluronic Acid in Inflammation and Tissue Regeneration
Wounds. 2016 Mar;28(3):78-88

Maytin E.V. (2016):

Hyaluronan: More than just a wrinkle filler
Glycobiology. 2016 Jun;26(6):553-9

Qiu Y.X. et al. (2016):

Influence of covering of auto-crosslinked sodium hyaluronate gel in combination with xenogenic acellular dermal matrix on healing of full-thickness skin defect wound in pig
Zhonghua Shao Shang Za Zhi. 2016 Sep 20;32(9):555-9

Shahraki K. et al. (2016):

Effects of Topical 1% Sodium Hyaluronate and Hydroxypropyl Methylcellulose in Treatment of Corneal Epithelial Defects
Med Hypothesis Discov Innov Ophthalmol. 2016 Winter; 5(4): 136–144

Silva C.R.. et al. (2016):

Injectable and tunable hyaluronic acid hydrogels releasing chemotactic and angiogenic growth factors for endodontic regeneration
Acta Biomater. 2018 Sep 1;77:155-171

Silva L. P. et al. (2016):

Neovascularization Induced by the Hyaluronic Acid-Based Spongy-Like Hydrogels Degradation Products
ACS Appl Mater Interfaces. 2016 Dec 14;8(49):33464-33474

Shin Y. C. et al. (2016):

Hyaluronic Acid/PLGA Core/Shell Fiber Matrices Loaded with EGCG Beneficial to Diabetic Wound Healing
Adv Healthc Mater. 2016 Dec;5(23):3035-3045

Wang Z. et al. (2016):

Evaluation of emulsion electrospun polycaprolactone/hyaluronan/epidermal growth factor nanofibrous scaffolds for wound healing
J Biomater Appl. 2016 Jan;30(6):686-98

Zhong J. et al. (2016):

Hyaluronate Acid-Dependent Protection and Enhanced Corneal Wound Healing against Oxidative Damage in Corneal Epithelial Cells
J Ophthalmol. ;2016:6538051

Borzacchiello A. et al. (2015):

Hyaluronic Acid Based Hydrogels for Regenerative Medicine Applications
Biomed Res Int. 2015;2015:871218

Catanzano O. et al. (2015):

Alginate-hyaluronan composite hydrogels accelerate wound healing process
Carbohydr Polym. 2015 Oct 20;131:407-14

Aya K.L., Stern R. (2014):

Hyaluronan in wound healing: rediscovering a major player
Wound Repair Regen. 2014 Sep-Oct;22(5):579-93

Bae M.S. et al. (2014):

Photo-cured hyaluronic acid-based hydrogels containing growth and differentiation factor 5 (GDF-5) for bone tissue regeneration. Bone. 2014 Feb;59:189-98

Cerqueira M.T. et al. (2014):

Human skin cell fractions fail to self- organize within a gellan gum/hyaluronic acid matrix but positively influence early wound healing
Tissue Eng Part A. 2014 May;20(9-10):1369-78

Domodarasamy M.. (2014):

Hyaluronan enhances wound repair and increases collagen III in aged dermal wounds.
Wound Repair Regen. Jul-Aug 2014;22(4):521-6

Frenkel J.S. (2014):

The role of hyaluronan in wound healing. Int Wound J. 2014 Apr;11(2):159-63

Fronza M. et al. (2014):

Hyaluronidase modulates inflammatory response and accelerates the cutaneous wound healing. PLoS One . 2014 Nov 13;9(11):e112297

Singleton P. A. et al. (2014):

Hyaluronan regulation of endothelial barrier function in cancer
Adv Cancer Res. 2014;123:191-209

Su Z. et al. (2014):

Enhancement of skin wound healing with decellularized scaffolds loaded with hyaluronic acid and epidermal growth factor
Mater Sci Eng C 2014; 44:440–448

Wu C. L. et al. (2013):

Hyaluronsäure-abhängiger Schutz gegen alkalisch verbrannte menschliche Hornhautzellen
Electrophoresis. 2013 Feb;34(3):388-96

Chen Q. et al. (2012):

The evaluation of two new hyaluronan hydrogels as nasal dressing in the rabbit maxillary sinus
Am J Rhinol Allergy. 2012 Mar-Apr;26(2):152-6

Colella G. et al. (2012):

Molecular insights into the effects of sodium hyaluronate preparations in keratinocytes
Clin Exp Dermatol. 2012 Jul;37(5):516-20

Ghazi K. et al. (2012):

Hyaluronan fragments improve wound healing on in vitro cutaneous model through P2X7 purinoreceptor basal activation: role of molecular weight
PLoS One. 2012;7(11):e48351

Hoffmann A. et al. (2012):

Role of Hyaluronic Acid Treatment in the Prevention of Keloid Scarring
J Am Coll Clin Wound Spec. 2012 Jun; 4(2): 23–31

Laznicek M. et al. (2012):

Preclinical evaluation of wound treatment with hyaluronan-iodine hydrogel
Wounds. 2012 Sep;24(9):267-74

Prosdocimi M., Bevilacqua C. (2012):

Exogene Hyaluronsäure und Wundheilung: eine aktualisierte Vision
Panminerva Med. 2012 Jun;54(2):129-35

Prosdocimi M., Bevilacqua C. (2012):

Impaired wound healing in diabetes: the rationale for clinical use of hyaluronic acid plus silver sulfadiazine
Minerva Med. 2012 Dec;103(6):533-9

Teh B. M. et al. (2012):

A review on the use of hyaluronic acid in tympanic membrane wound healing
Expert Opin Biol Ther. 2012 Jan;12(1):23-36

Anilkumar T.V. et al. (2011):

Advantages of hyaluronic acid as a component of fibrin sheet for care of acute wound
Biologicals. 2011 Mar;39(2):81-8

Ardizzoni A. et al. (2011):

Influence of hyaluronic acid on bacterial and fungal species, including clinically relevant opportunistic pathogens
J Mater Sci Mater Med. 2011 Oct;22(10):2329-38

Bae M.S. et al. (2011):

Photo-cured hyaluronic acid-based hydrogels containing simvastatin as a bone tissue regeneration scaffold
Biomaterials. 2011 Nov;32(32):8161-71

Cermelli C. et al. (2011):

In vitro evaluation of antiviral and virucidal activity of a high molecular weight hyaluronic acid
Virol J. 2011 Mar 25;8:141

Cutting K.F. (2011):

Wound healing through synergy of hyaluronan and an iodine complex
J Wound Care. 2011 Sep;20(9):424, 426, 428-30

Jiang D. et al. (2011):

Hyaluronan as an immune regulator in human diseases
Physiol Rev. 2011 Jan;91(1):221-64

Gall Y. et al. (2011):

Hyaluronic acid: structure, metabolism and implication in cicatrisation
Ann Dermatol Venereol. 2010 Apr;137 Suppl 1:S30-9

Gao F. et al. (2010):

Hyaluronan oligosaccharides promote excisional wound healing through enhanced angiogenesis
Matrix Biol. 2010 Mar;29(2):107-16

Lataillade J.J. et al. (2010):

Implication of hyaluronic acid in normal and pathological angiogenesis. Application for cellular engineering
Ann Dermatol Venereol. 2010 Apr;137 Suppl 1:S15-22

Slavkovsky R. et al. (2010):

Effects of hyaluronan and iodine on wound contraction and granulation tissue formation in rat skin wounds. Clin Exp Dermatol. 2010 Jun;35(4):373-9

Pasquinelli G. et al. (2009):

Architectural organization and functional features of early endothelial progenitor cells cultured in a hyaluronan-based polymer scaffold
Tissue Eng Part A. 2009 Sep;15(9):2751-62

Volpi N. et al. (2009):

Role, metabolism, chemical modifications and applications of hyaluronan
Curr Med Chem. 2009;16(14):1718-45

Zavan B. et al. (2009):

Hyaluronan based porous nano-particles enriched with growth factors for the treatment of ulcers: a placebo-controlled study
J Mater Sci Mater Med. 2009 Jan;20(1):235-47

David-Raoudi M. et al. (2008):

Differential effects of hyaluronan and its fragments on fibroblasts: relation to wound healing
Wound Repair Regen. 2008 Mar-Apr;16(2):274-87

Ievdokimova N. (2008):

Hyaluronic acid, receptor CD44, and their role in diabetic complications
Ukr Biokhim Zh (1999). 2008 Sep-Oct;80(5):5-44

Kogan G.. et al. (2008):

Hyaluronic Acid: Its Function and Degradation in in vivo Systems
Studies in Natural Products Chemistry 2008; 34:789-882

Olczyk P. et al. (2008):

Hyaluronan: structure, metabolism, functions, and role in wound healing
Postepy Hig Med Dosw (Online). 2008 Dec 2;62:651-9

Pardue E. L. et al. (2008):

Role of hyaluronan in angiogenesis and its utility to angiogenic tissue engineering
Organogenesis. 2008 Oct;4(4):203-14

Jiang D. et al. (2007):

Hyaluronan in tissue injury and repair
Annu Rev Cell Dev Biol. 2007;23:435-61

Meran S. et al. (2007):

Involvement of hyaluronan in regulation of fibroblast phenotype
J Biol Chem. 2007 Aug 31;282 (35):25687-97

Myers S. R. et al. (2007):

Hyalomatrix: a temporary epidermal barrier, hyaluronan delivery, and neodermis induction system for keratinocyte stem cell therapy
Tissue Eng. 2007 Nov;13(11):2733-41

Dechert T. A. et al. (2007):

Hyaluronan in human acute and chronic dermal wounds
Wound Repair Regen. May-Jun 2006;14(3):252-8

Frankova J. et al. (2007):

The effect of hyaluronan combined with KI3 complex (Hyiodine wound dressing) on keratinocytes and immune cells. J Mater Sci Mater Med. 2006 Oct;17(10):891-8

Brown J. A., Jones S. A. (2005):

Hyaluronic acid: a unique topical vehicle for the localized delivery of drugs to the skin
JEADV (2005) 19, 308–318

Brown J.A. (2004):

The role of hyaluronic acid in wound healing's proliferative phase
J Wound Care. 2004 Feb;13(2):48-51

Maytin E.V. et al. (2004):

Hyaluronan Participates in the Epidermal Response to Disruption of the Permeability Barrier in Vivo. Am J Pathol. 2004 Oct; 165(4): 1331–1341

Moseley R. et al. (2003):

Comparison of the antioxidant properties of wound dressing materials--carboxymethylcellulose, hyaluronan benzyl ester and hyaluronan, towards polymorphonuclear leukocyte-derived reactive oxygen species
Biomaterials. 2003 Apr;24(9):1549-57

Uccioli L. et al. (2003):

A clinical investigation on the characteristics and outcomes of treating chronic lower extremity wounds using the tissuetech autograft system
Int J Low Extrem Wounds. 2003 Sep;2(3):140-51

Moseley R. et al. (2002):

Comparison of the antioxidant properties of HYAFF-11p75, AQUACEL and hyaluronan towards reactive oxygen species in vitro
Biomaterials 2002; 23/10:2255-2264

Trabucchi E. et al. (2002):

Low molecular weight hyaluronic acid prevents oxygen free radical damage to granulation tissue during wound healing
Int J Tissue React. 2002;24(2):65-71

Galassi G. et al. (2000):

In vitro reconstructed dermis implanted in human wounds: degradation studies of the HA-based supporting scaffold
Biomaterials 2000; 21/21:2183-2191

Brun P. et al. (1999):

In vitro reconstructed tissues on hyaluronan-based temporary scaffolding
Journal of Materials Science: Materials in Medicine 10, 683–688 (1999)

Chen W.Y., Abatangelo G. (1999):

Functions of hyaluronan in wound repair
Wound Repair Regen. 1999 Mar-Apr;7(2):79-89

Mast B.A. et al. (1995):

Hyaluronic acid degradation products induce neovascularization and fibroplasia in fetal rabbit wounds
Wound Repair Regen. Jan-Mar 1995;3(1):66-72

Lorenz H. P. et al. (1993):

Scarless skin wound repair in the fetus
West J Med. 1993 Sep; 159(3): 350–355

Mast B. A. et al. (1993):

Hyaluronic acid modulates proliferation, collagen and protein synthesis of cultured fetal fibroblasts
Matrix. 1993 Nov;13(6):441-6

Mast B. A. et al. (1992):

In vivo degradation of fetal wound hyaluronic acid results in increased fibroplasia, collagen deposition, and neovascularization
Plast Reconstr Surg. 1992 Mar;89(3):503-9

King S. R. et al. (1991):

Beneficial actions of exogenous hyaluronic acid on wound healing
Surgery. 1991 Jan;109(1):76-84

Longaker M.T. et al. (1991):

Studies in fetal wound healing. V. A prolonged presence of hyaluronic acid characterizes fetal wound fluid
Ann Surg. 1991 Apr;213(4):292-6

Longaker M.T. et al. (1990):

Studies in fetal wound healing, VII. Fetal wound healing may be modulated by hyaluronic acid stimulating activity in amniotic fluid
J Pediatr Surg. 1990 Apr;25(4):430-3

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