Klinische Vergleichsstudien Hyaluronsäure

Cetinkaya O.A. et al. (2020): 

Treatment of hard-to-heal leg ulcers with hyaluronic acid, sodium alginate and negative pressure wound therapy.
J Wound Care. 2020 Jul 2;29(7):419-423.

De Angelis B. et al. (2019): 

Wound Healing: In Vitro and In Vivo Evaluation of a Bio-Functionalized Scaffold Based on Hyaluronic Acid and Platelet-Rich Plasma in Chronic Ulcers.
J Clin Med. 2019 Sep 18;8(9) 

Yıldırım S. et al. (2018): 

Effect of topically applied hyaluronic acid on pain and palatal epithelial wound healing: An examiner-masked, randomized, controlled clinical trial.
J Periodontol. 2018 Jan;89(1):36-45. 

Scalise A. et al. (2017): 

Enzymatic debridement: is HA- collagenase the right synergy? Randomized double-blind controlled clinical trial in venous leg ulcers
Eur Rev Med Pharmacol Sci. 2017 Mar;21(6):1421-1431 

Alvarez O.M. et al. (2017): 

Venous Ulcers Treated With a Hyaluronic Acid Extracellular Matrix and Compression Therapy: Interim Analysis of a Randomized Controlled Trial
Wounds 2017;29(7):E51–E54 

Lee M. et al.  (2016): 

Hyaluronic acid dressing (Healoderm) in the treatment of diabetic foot ulcer: A prospective, randomized, placebo-controlled, single-center study
Wound Repair Regen. 2016 May;24(3):581-8 

You H.J. et al. (2014) 

Randomised controlled clinical trial for autologous fibroblast-hyaluronic acid complex in treating diabetic foot ulcers
J Wound Care. 2014 Nov;23(11):521-2, 524, 526-30 

Humbert P. et al. (2013): 

Efficacy and safety of a gauze pad containing hyaluronic acid in treatment of leg ulcers of venous or mixed origin: a double-blind, randomised, controlled trial
Int Wound J. 2013 Apr;10(2):159-66 

Dereure O. et al. (2012): 

Efficacy and safety of hyaluronic acid in treatment of leg ulcers: a double- blind RCT
J Wound Care. 2012 Nov;21(11):539-42, 544, 546-7 

Dereure O. et al. (2012): 

RCT to evaluate a hyaluronic acid containing gauze pad in leg ulcers of venous or mixed aetiology
J Wound Care. 2012 Mar;21(3):131-2, 134-6, 138-9 

Uccioli L. et al. (2011): 

Two-step autologous grafting using HYAFF scaffolds in treating difficult diabetic foot ulcers: results of a multicenter, randomized controlled clinical trial with long-term follow-up
Int J Low Extrem Wounds. 2011 Jun;10(2):80-5 

Caravaggi C. et al. (2011) 

Wound Bed Preparation With a Dermal Substitute (Hyalomatrix® PA) Facilitates Re-epithelialization and Healing: Results of a Multicenter, Prospective, Observational Study on Complex Chronic Ulcers

Wounds. 2011 Aug;23(8):228-35 

Abbruzzese L. et al. (2009): 

Effectiveness and safety of a novel gel dressing in the management of neuropathic leg ulcers in diabetic patients: a prospective double-blind randomized trial

Int J Low Extrem Wounds. 2009 Sep;8(3):134-40. 

Lee J.H. et al.  (2008): 

The efficacy of topical 0.2% hyaluronic acid gel on recurrent oral ulcers: comparison between recurrent aphthous ulcers and the oral ulcers of Behçet's disease

J Eur Acad Dermatol Venereol. 2008 May;22(5):590-5 

Meaume S. et al. (2008): 


Efficacy and tolerance of a hydrocolloid dressing containing hyaluronic acid for the treatment of leg ulcers of venous or mixed origin. 

Curr Med Res Opin 24(10):2729–2739.

Costagliola M., Agrosì M. (2005): 

Second-degree burns: a comparative, multicenter, randomized trial of hyaluronic acid plus silver sulfadiazine vs. silver sulfadiazine alone
Curr Med Res Opin. 2005 Aug;21(8):1235-40 

Koller J. (2004): 

Topical treatment of partial thickness burns by silver sulfadiazine plus hyaluronic acid compared to silver sulfadiazine alone: a double-blind, clinical study
Drugs Exp Clin Res. 2004;30(5-6):183-90 

Taddeucci P. et al. (2004): 

An evaluation of Hyalofill-F plus compression bandaging in the treatment of chronic venous ulcers
J Wound Care. 2004 May;13(5):202-4 

Caravaggi C. et al. (2003): 

HYAFF 11-based autologous dermal and epidermal grafts in the treatment of noninfected diabetic plantar and dorsal foot ulcers: a prospective, multicenter, controlled, randomized clinical trial
Diabetes Care. 2003 Oct;26(10):2853-9 

Ortonne J.P. (2001): 

Comparative study of the activity of hyaluronic acid and dextranomer in the treatment of leg ulcers of venous origin
Ann Dermatol Venereol. 2001 Mar;Suppl:13-6